| 1 | The Secret Life of Pets | 2016-06-18 | $75M | $373.68M | 4.98 |
| 2 | Minions | 2015-06-17 | $74M | $342.25M | 4.62 |
| 3 | Fantastic Beasts and Where to Find Them | 2016-11-16 | $180M | $242.79M | 1.35 |
| 4 | Doctor Strange | 2016-10-25 | $180M | $242.04M | 1.34 |
| 5 | Fantastic Beasts: The Crimes of Grindelwald | 2018-11-14 | $200M | $168.66M | 0.84 |
| 6 | A Quiet Place: Day One | 2024-06-26 | $67M | $145.73M | 2.18 |
| 7 | Ocean's Eight | 2018-06-07 | $70M | $143.38M | 2.05 |
| 8 | Ghostbusters | 2016-07-14 | $144M | $131.68M | 0.91 |
| 9 | Sully | 2016-09-07 | $60M | $126.42M | 2.11 |
| 10 | Teenage Mutant Ninja Turtles: Mutant Mayhem | 2023-07-31 | $75M | $122.46M | 1.63 |
| 11 | Scream VI | 2023-03-08 | $35M | $113.86M | 3.25 |
| 12 | Little Women | 2019-12-25 | $40M | $108.1M | 2.70 |
| 13 | Hustlers | 2019-09-12 | $20M | $107.46M | 5.37 |
| 14 | A Complete Unknown | 2024-12-25 | $65M | $76.4M | 1.18 |
| 15 | Uncut Gems | 2019-08-30 | $19M | $50.02M | 2.63 |
| 16 | Isn't It Romantic | 2019-02-13 | $31M | $48.79M | 1.57 |
| 17 | How to Be Single | 2016-02-08 | $38M | $47.54M | 1.25 |
| 18 | Lyle, Lyle, Crocodile | 2022-10-07 | $50M | $47.46M | 0.95 |
| 19 | Uncle Drew | 2018-06-27 | $19M | $42.47M | 2.24 |
| 20 | West Side Story | 2021-12-08 | $100M | $39.33M | 0.39 |
| 21 | Brooklyn | 2015-10-20 | $11M | $38.22M | 3.47 |
| 22 | Materialists | 2025-06-12 | $20M | $37.2M | 1.86 |
| 23 | Collateral Beauty | 2016-12-15 | $36M | $31.02M | 0.86 |
| 24 | 21 Bridges | 2019-10-24 | $33M | $29.24M | 0.89 |
| 25 | The Last Witch Hunter | 2015-10-21 | $90M | $27.89M | 0.31 |
| 26 | Florence Foster Jenkins | 2016-05-06 | $29M | $27.57M | 0.95 |
| 27 | Caught Stealing | 2025-08-26 | $40M | $20.21M | 0.51 |
| 28 | Cabrini | 2024-03-07 | $50M | $20.01M | 0.40 |
| 29 | The Glass Castle | 2017-08-11 | $9M | $17.27M | 1.92 |
| 30 | Norm of the North | 2016-01-14 | $7M | $17.06M | 2.44 |
| 31 | If Beale Street Could Talk | 2018-12-14 | $12M | $14.92M | 1.24 |
| 32 | Three Identical Strangers | 2018-06-29 | $0 | $12.32M | N/A |
| 33 | The Kitchen | 2019-08-08 | $38M | $12.18M | 0.32 |
| 34 | Bros | 2022-09-30 | $22M | $12.13M | 0.55 |
| 35 | Café Society | 2016-05-11 | $30M | $11.1M | 0.37 |
| 36 | Greta | 2019-02-28 | $0 | $10.52M | N/A |
| 37 | Saturday Night | 2024-12-14 | $0 | $10.23M | N/A |
| 38 | The Walk | 2015-09-30 | $35M | $9.74M | 0.28 |
| 39 | In the Heights | 2021-06-10 | $55M | $7.61M | 0.14 |
| 40 | Boy Erased | 2018-09-24 | $15M | $6.79M | 0.45 |
| 41 | The Goldfinch | 2019-09-12 | $40M | $5.33M | 0.13 |
| 42 | Gotti | 2018-06-14 | $10M | $4.29M | 0.43 |
| 43 | Boogie | 2021-03-05 | $20M | $4.18M | 0.21 |
| 44 | The Apprentice | 2024-10-09 | $16M | $4.15M | 0.26 |
| 45 | Tom & Jerry | 2021-02-10 | $50M | $4M | 0.08 |
| 46 | Friends 25th: The One with the Anniversary | 2019-09-23 | $0 | $2.88M | N/A |
| 47 | You Were Never Really Here | 2017-11-08 | $17M | $2.52M | 0.15 |
| 48 | Mistress America | 2015-08-14 | $0 | $2.42M | N/A |
| 49 | Die Hard | 1988-07-15 | $28M | $2.37M | 0.08 |
| 50 | Good Time | 2017-08-11 | $0 | $2.01M | N/A |